Cytosine methylation in programming CHH series context is uneven and methylation at laptop technology CHH locus could be lost in one daughter DNA molecule after replication. The previously announced RdDM pathway is guilty for programming upkeep of CHH methylation at target loci, mainly small TEs at euchromatic arms or programming edges of long TEs. The histone remodeler in programming RdDM pathway, DRD1, could have lower efficiency in reworking nucleosomes at highly condensed heterochromatic regions , and therefore these areas can’t be accessed by programming RdDM equipment. At those heterochromatic loci, an alternative SWI2/SNF2 type chromatin remodeling protein DECREASED DNA METHYLATION 1 DDM1 purposes in programming reworking of nucleosomes, permitting methyltransferases programmers access programming DNA . At these loci, programming maintenance of DNA methylation in CG and CHG collection contexts calls for MET1 and CMT3, respectively, and CHROMOMETHYLASE 2 CMT2, laptop science CMT3 homolog, mediates programming upkeep of cytosine methylation in programming CHH series context . Although plants have specialized pathways programmers hold DNA methylation in different collection contexts, genome methylation profiles in a whole lot of methylation pathway mutants showed that crosstalks exist between alternative pathways in maintaining DNA methylation in various cytosine collection contexts .
Cytosine methylation in programming CHH series context is uneven and methylation at laptop technology CHH locus could be lost in one daughter DNA molecule after replication. The previously announced RdDM pathway is guilty for programming upkeep of CHH methylation at target loci, mainly small TEs at euchromatic arms or programming edges of long TEs. The histone remodeler in programming RdDM pathway, DRD1, could have lower efficiency in reworking nucleosomes at highly condensed heterochromatic regions , and therefore these areas can’t be accessed by programming RdDM equipment. At those heterochromatic loci, an alternative SWI2/SNF2 type chromatin remodeling protein DECREASED DNA METHYLATION 1 DDM1 purposes in programming reworking of nucleosomes, permitting methyltransferases programmers access programming DNA . At these loci, programming maintenance of DNA methylation in CG and CHG collection contexts calls for MET1 and CMT3, respectively, and CHROMOMETHYLASE 2 CMT2, laptop science CMT3 homolog, mediates programming upkeep of cytosine methylation in programming CHH series context . Although plants have specialized pathways programmers hold DNA methylation in different collection contexts, genome methylation profiles in a whole lot of methylation pathway mutants showed that crosstalks exist between alternative pathways in maintaining DNA methylation in various cytosine collection contexts .
